Journal of affective disordersHumansMajor Depressive DisorderHashimoto DiseaseGene Expression ProfilingTranscriptome
Major depressive disorder and Hashimoto's thyroiditis: Shared immunometabolic signatures revealed by integrative transcriptomics.
Li Zhang, Kefan Chen, Jie Yao, Jun Zeng, Yuting Qiu, Yan Wei, Kenji Hashimoto, Xiangyu Zhou
Published: 202610.1016/j.jad.2025.120827
Abstract
Major depressive disorder (MDD) and Hashimoto's thyroiditis (HT) frequently co-occur, yet their shared molecular underpinnings remain unclear. We performed an integrative transcriptomics analysis combining transcriptomic profiling, immune cell deconv…
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