Journal of affective disordersHumansMajor Depressive DisorderMaleFemaleMagnetic Resonance Imaging
Default mode network and reward network dysconnectivity among young individuals with major depressive disorder with and without systemic low-grade inflammation.
Ya-Mei Bai, Li-Kai Cheng, Wei-Chen Lin, Ju-Wei Hsu, Li-Fen Chen, Pei-Chi Tu, Cheng-Ta Li, Shih-Jen Tsai, Li-Chi Chen, Tung-Ping Su, Mu-Hong Chen
Published: 202610.1016/j.jad.2025.120491
Abstract
BACKGROUND: Evidence indicates that up to 30 % of patients with major depressive disorder (MDD) exhibit low-grade inflammation (LGI). However, the effect of LGI on functional connectivity (FC) involving the default mode network (DMN) and reward netwo…
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