Journal of affective disordersHumansMendelian Randomization AnalysisGastrointestinal MicrobiomeMaleFemale
Blood metabolites mediate gut microbiota effects on depression: A Mendelian randomization study.
Yao-Wen Zhang, Sha-Sha Zhao, Xue-Yan Li, Huan-Zhen Liu
Published: 202610.1016/j.jad.2025.120478
Abstract
BACKGROUND: Accumulating evidence indicates that gut microbiota (GM) influence depression via gut-brain axis signaling, yet the causal relationships and underlying mechanisms are not fully understood. We conducted bidirectional Mendelian randomizatio…
Preview only. Read the full abstract at the source