Journal of affective disordersHumansMaleFemaleCircadian RhythmNuclear Receptor Subfamily 1
Higher morning NR1D1 (REV-ERBΑα) expression, robust circadian activity, and less light at night predict lower depression scores in arctic residents.
Denis Gubin, Sergey Kolomeichuk, Konstantin Danilenko, Oliver Stefani, Alexander Markov, Ivan Petrov, Kirill Voronin, Marina Mezhakova, Mikhail Borisenkov, Aislu Shigabaeva, Julia Boldyreva, Julianna Petrova, Dietmar Weinert, Germaine Cornelissen
Published: 202610.1016/j.jad.2025.120417
Abstract
BACKGROUND: Depression poses a challenge in high-latitude regions. Research suggests links between light exposure, clock genes, and mental health. Understanding these connections is crucial, given light's influence on circadian rhythms and potential…
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