The Journal of allergy and clinical immunology
Exome Sequencing Reveals rare Loss-of-Function Mutations in FLG and Immune Genes in Multi-Food Allergic Patients.
Anas M Khanshour, Cynthia Haddad, Steve Meregini, Mellisa Zamudio, Amy Arneson, Christopher Parrish, Jonathan R Rios, J Andrew Bird, Jeffrey A SoRelle
Published: 202610.1016/j.jaci.2026.01.001
Abstract
BACKGROUND: Studies of twins, parents, and families have demonstrated a strong heritable role in allergy and food allergy in particular (60-80%). However, genetic loci identified in previous genome wide association studies (GWAS) focused on common va…
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