The Journal of allergy and clinical immunology
Transcriptome-wide association study of sex effects identifies sex-specific nasal epithelial gene expression profiles for total IgE.
Molin Yue, Yidan Sun, Yueh Ying Han, Glorisa Canino, Erick Forno, Judith M Vonk, Elin T G Kersten, Wei Chen, Gerard H Koppelman, Juan C Celedón
Published: 202510.1016/j.jaci.2025.12.1003
Abstract
BACKGROUND: Asthma is the most common chronic respiratory disease in children, with known sex differences in prevalence and severity that shift after puberty. Total IgE, a marker of type 2-high asthma, also differs by sex and age and may contribute t…
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