JACC. Clinical electrophysiology
Low-Dose Cardiac Radiation Improves Electrical Function and Reduces Ventricular Arrhythmogenesis in Mice With Nonischemic Cardiomyopathy.
Devaki A Abhyankar, Marissa R Pennino, Lauren N Pedersen, Felicia Grogan, Amanda Klass, Carla Valenzuela Ripoll, Sherwin Ng, Zhen Guo, Hamidreza Hajirezaei, Stacey L Rentschler, Clifford G Robinson, Phillip S Cuculich, Joel D Schilling, Carmen Bergom, Ali Javaheri
Published: 202510.1016/j.jacep.2025.10.034
Abstract
BACKGROUND: Clinical cardiac radiation therapy (RT-25 Gy) decreases ventricular tachycardia (VT). Nonischemic cardiomyopathy (NICM) murine studies showed improved left ventricular (LV) ejection fraction (LVEF) with low-dose RT (LDRT-5 Gy), attributed…
Preview only. Read the full abstract at the source