Journal of the American College of CardiologyHumansThrombolytic TherapyFibrinolytic AgentsThromboembolismForecasting
Fibrinolytic Therapy for Thromboembolic Diseases: Approved Indications and Future Directions.
Sina Rashedi, Hannah Leyva, Nada Hamade, Mariana B Pfeferman, Luis Ortega-Paz, Parham Sadeghipour, Azita H Talasaz, Michelle L O'Donoghue, David Jimenez, Manuel Monreal, Christopher D Anderson, Mitchell S V Elkind, Irene M Lang, Jeffery I Weitz, Samuel Z Goldhaber
Published: 202510.1016/j.jacc.2025.07.061
Abstract
Fibrinolytic therapy plays a pivotal role in the management of thromboembolic diseases by promoting plasmin-mediated fibrin degradation and vessel recanalization, which frequently comes at the cost of increased risk of hemorrhagic events, including i…
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