Trends in immunologyHumansBreast NeoplasmsFemaleTumor MicroenvironmentReceptors
A novel mechanism of immunoevasion by ER+ breast cancer.
Claudia Galassi, Lorenzo Galluzzi
Published: 202610.1016/j.it.2025.12.003
Abstract
Estrogen receptor (ER)+ breast malignancies are poorly infiltrated by immune cells, hence exhibiting limited sensitivity to immune checkpoint inhibitors (ICIs). Recent data from Palomeque et al. demonstrate that ER signaling actively contributes to s…
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