Trends in immunologyAnimalsHumansChromatinExtracellular TrapsNeutrophils
Myeloperoxidase transforms chromatin into an immune weapon.
Hannah Garner
Published: 202510.1016/j.it.2025.11.001
Abstract
Burn et al. reveal a previously unrecognised, non-catalytic function of myeloperoxidase (MPO) in neutrophil extracellular trap (NET) formation; integrating super-resolution microscopy and biochemical approaches, they demonstrated that MPO's oligomeri…
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