International immunopharmacology
Trimethyltin chloride (TMT) - induced vascular injury through ubiquitination proteasome pathway - regulated GPX4 degradation.
Yan Song, Mi Chen, Chen Wu, Leiming Yang, Qiyu Sun, Shuang Guo, Huiting He, Qi Huang, Xiying Guo, Youzhi Zhang
Published: 202610.1016/j.intimp.2026.116250
Abstract
Trimethyltin chloride (TMT) is a highly toxic organotin pollutant commonly found in the environment, posing serious risks to humans and animals. To explore the potential toxicity mechanism of TMT on vascular systems, we developed models exposing vasc…
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