International immunopharmacology
Agmatine ameliorates poly(I:C)-induced lung injury through IL-10/STAT3-dependent reprogramming of macrophage inflammatory responses.
Zhen Sun, Xiaochang Zhang, Sha Liao, Zhe Zhou
Published: 202610.1016/j.intimp.2026.116247
Abstract
The emerging field of immunometabolism posits that endogenous metabolites are pivotal regulators of immune responses, yet their therapeutic exploitation remains nascent. Investigating this paradigm in lung injury, we observed that agmatine, a decarbo…
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