International immunopharmacologyAnimalsReperfusion InjuryPPAR gammaMaleRats
Oleanolic acid alleviates intestinal injury after hepatic ischemia-reperfusion under steatosis via PPARG-dependent M2 macrophage polarization.
Yilin Pi, Yuxin Wang, Qin Guo, Weiping Zheng, Huiyuan Zhou, Lamei Deng, Ningxia Xu, Hongli Song
Published: 202610.1016/j.intimp.2026.116162
Abstract
Liver transplantation with steatotic donor livers is often complicated by ischemia-reperfusion injury (IRI), leading to intestinal dysfunction, and reduced long-term survival. This study investigates the protective effects of oleanolic acid (OA), a g…
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