International immunopharmacologyAnimalsLycopeneAcute Kidney InjuryMaleMice
Lycopene protects against acute kidney injury by suppressing PARP/NOTCH-mediated inflammation.
Xiao-Wei Hu, Yu-Qing Wang, Xiang-Yu Li, Xiao-Yu Shen, Run-Run Shan, Ju-Tao Yu, He-Ping Cai, Xiao-Ming Meng, Qin Yang
Published: 202610.1016/j.intimp.2025.116136
Abstract
Acute kidney injury (AKI) is a clinical syndrome caused by diverse etiologies. It is characterized by a rapid decline in renal function, marked increases in serum creatinine and urea nitrogen levels, and excessive recruitment of inflammatory cells. A…
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