International immunopharmacologyAnimalsAlzheimer DiseaseThymosinNeuritesMice
Thymosin β4-derived peptides alleviate neuroinflammation and neurite atrophy in both in vitro models and in vivo 5 × FAD mice: A potential therapy for memory improvement in Alzheimer's disease.
Haiyan Ou, Ruiye Chen, Longjian Zhou, Yi Zhang, Shuai Zhao, Zhiyou Yang
Published: 202610.1016/j.intimp.2025.116097
Abstract
Alzheimer's disease (AD) is a progressive neurodegenerative disorder defined by neuroinflammation, neurite atrophy, and cognitive decline. This study explored the therapeutic potential of Thymosin β4 (Tβ4)-derived peptides (TB500 and Ac-SDKP) in miti…
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