International immunopharmacologyAnimalsReceptorsPurinergic P2X7Calcitonin Gene-Related PeptideEpilepsy
CGRP alleviates epilepsy via JAK1-STAT1-P2RX7 signaling: a novel neuroprotective axis targeting neuronal damage.
Yuxiang Li, Jixiang Sun, Yanmin Lyu, Mengying Huang, Chunxiao Du, Meng Liang, Junrui Chen, Jiawen Lu, Ge Li, Zhiding Wang, Gencheng Han
Published: 202610.1016/j.intimp.2025.116080
Abstract
BACKGROUND: Calcitonin gene-related peptide (CGRP), a 37-amino-acid neuropeptide, is widely distributed in the central and peripheral nervous systems and participates in regulating various physiological and pathological processes such as vasodilation…
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