International immunopharmacologyHumansNucleotidyltransferasesMembrane ProteinsNeoplasmsDrug Delivery Systems
"Emerging precision drug delivery systems for controlled activation of the cGAS-STING pathway in Cancer, infection, and autoimmune disorders".
Gajjala Pavani, Gurubasavaraja Swamy Purawarga Matada, Abhishek Ghara, Arghya Paik, Anubhav Richard David, Changala Kavyasree
Published: 202610.1016/j.intimp.2025.116052
Abstract
The cyclic GMP-AMP synthase Stimulator of Interferon Genes (cGAS-STING) pathway is a key component of innate immunity, detecting cytosolic DNA and initiating type I interferon (IFN-I) responses that shape downstream adaptive immunity. Owing to its ce…
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