International immunopharmacologyAnimalsMesenchymal Stem Cell TransplantationInjectionsIntra-ArticularHumans
Timing of intra-articular injection of adipose-derived mesenchymal stem cells affects cartilage integrity and IL-18 expression in spontaneous osteoarthritis: A preclinical study.
Mei-Feng Chen, Yung-Heng Hsu, Yu-Chih Lin, Chih-Chien Hu, Yu-Tien Chiu, Steve Wen-Neng Ueng, Yuhan Chang
Published: 202610.1016/j.intimp.2025.115964
Abstract
Osteoarthritis (OA) is a progressive joint disease primarily characterized by cartilage degradation. A phase I/II clinical trial demonstrated the therapeutic efficacy of a human adipose-derived mesenchymal stem cell (ADMSC) product in patients with k…
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