International immunopharmacologyAnimalsCatechinGastrointestinal MicrobiomeInflammasomesNLR Family
EGCG alleviates colitis in inflammatory bowel disease via gut microbiota-derived LCA and inhibition of NLRP3 inflammasome.
Kaiqiang Zhong, Yizhou Yao, Bo Shi, Si Li, Yirui Zhao, Xuchao Wang, Chunli Zhou, Bin Wang, Xinyu Shao, Xinguo Zhu
Published: 202610.1016/j.intimp.2025.115962
Abstract
The incidence of inflammatory bowel disease (IBD) is increasing worldwide and has caused an enormous economic burden. As the main polyphenolic bioactive substance in green tea, epigallocatechin-3-gallate (EGCG) exerts anti-inflammatory and antioxidan…
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