International immunopharmacologyHumansAutophagy-Related Protein-1 HomologAutophagyPyroptosisAnimals
The AMPK/ULK1/autophagy pathway: FGF23's weapon against GSDME-mediated pyroptosis in folic acid-induced acute kidney injury.
Lina Zhang, Limeng Wang, Baolan Yan, Ning Wang, Mengfan Li, Wenna Liu, Yanliang Wang, Lei Yan, Huixia Cao, Fengmin Shao, Wei Qin
Published: 202610.1016/j.intimp.2025.115937
Abstract
Acute kidney injury (AKI) is a common critical illness in clinical settings. Fibroblast growth factor 23 (FGF23) levels increase rapidly after AKI; however, the role of FGF23 in AKI remains unclear. We investigated the function and underlying mechani…
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