International immunopharmacologyAsthmaAnimalsHumansTh2 CellsMice
L-Citrulline inhibits Th2 cell activation via PLAC8 mediated autophagy and L-Citrulline depletion to alleviate pediatric asthma.
Tian Tian, Ning Wang, Fangli Jing, Ning Wang, Weiwei Zhi, Xiaoyuan Zhu, Li Liu
Published: 202610.1016/j.intimp.2025.115880
Abstract
Asthma is a common childhood chronic respiratory disease characterized by chronic airway inflammation.CD4+ Th2 cells drive eosinophil-mediated airway inflammation, which plays a pathogenic role in asthma. L-Citrulline(L-Cit) is a naturally occurring…
Preview only. Read the full abstract at the source