International immunopharmacologyChondrocytesAnimalsHumansOsteoarthritisCellular Senescence
Rhapontigenin inhibits inflammation and senescence of chondrocytes from patients with osteoarthritis by targeting INHBA.
Fan Su, Chenxi Peng, Shuoyang Zhang, Simin Chen, Kai Sun, Suling Liu, Huijuan Hu, Ruiru Li, Haonan Chen, Liuqin Liang, Youjun Xiao, Hanshi Xu
Published: 202610.1016/j.intimp.2025.115808
Abstract
OBJECTIVES: Rhapontigenin (RHAP), a natural small molecular stilbenoid extracted from Chinese herbal medicine Rhubarb, exhibits anti-inflammatory, antioxidant, antibacterial effects and protection on heart and nerve. However, its role in the treatmen…
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