International immunopharmacologyAnimalsChemokine CX3CL1CX3C Chemokine Receptor 1Brain InjuriesTraumatic
CX3CL1 attenuates neurological deficit and neuroinflammation through CX3CR1/p38 MAPK/ERK1/2 signaling pathway in traumatic brain injury.
Hao Zhu, Yangyi Cao, Xionghui Chen, Ningbo Xu, Yuqian Zhou, Peng Yang, Feng Xu, Jianfeng Ji
Published: 202610.1016/j.intimp.2025.115765
Abstract
BACKGROUND: Traumatic brain injury (TBI) induces a complex cascade of secondary pathological events, including neuroinflammation and oxidative stress, which substantially contribute to neuronal damage and long-term neurological deficits. The chemokin…
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