International immunopharmacologyHumansCarcinomaHepatocellularLiver NeoplasmsMitophagy
NDUFAB1 promotes hepatocellular carcinoma progression by disrupting mitochondrial homeostasis and mitophagy pathway.
Zhaonv Yao, Xianyi Tan, Huanyu Cui, Hongjun Liang, Ating Zhong, Yuxuan Man, Tingzhuang Yi, Zhengbao Zhang, Xuefeng Guo, Shengkui Tan, Xiaonian Zhu
Published: 202510.1016/j.intimp.2025.115664
Abstract
NADH: ubiquinone oxidoreductase subunit AB1 (NDUFAB1), a critical factor of mitochondrial complex I in electron transport chain, is essential for cellular energy metabolism; however, its specific functions and mechanisms in hepatocellular carcinoma (…
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