International immunopharmacologyAnimalsNF-E2-Related Factor 2FerroptosisIsothiocyanatesOxidative Stress
Enhancing myocardial injury recovery: Nrf2 activation by sulforaphane regulates ferroptosis and oxidative stress in takotsubo-like models.
Yuxi Huang, Wenyi Tang, Mei Xu, Liyun Luo, Tou Kun Chong, Qianglin Guan, Kaizhuang Huang, Kan Liu, Cunxue Pan, Jian Chen
Published: 202510.1016/j.intimp.2025.115659
Abstract
Takotsubo syndrome (TTS), once considered benign, can cause life-threatening myocardial injury. Although oxidative stress and ferroptosis are implicated in its pathogenesis, targeted therapies are not available for TTS. We demonstrate that sulforapha…
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