International immunopharmacologyFerroptosisCarcinomaHepatocellularHumansLiver Neoplasms
Arsenic trioxide enhances the inhibitory effect of lenvatinib on hepatocellular carcinoma through HMOX1-mediated ferroptosis.
Shufang Liang, Guokai Huang, Meihuan Fu, Yuanrong Shi, Xiaoyu Tu, Wanfu Lin, Jianhui Tian, Xiaofeng Zhai, Binbin Cheng
Published: 202510.1016/j.intimp.2025.115656
Abstract
Currently, Lenvatinib, a tyrosine kinase inhibitor, is used as a first-line treatment for advanced hepatocellular carcinoma (HCC), but its efficacy remains unsatisfactory. Therefore, we investigated the effect of Lenvatinib in combination with Arseni…
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