International immunopharmacologyHumansProto-Oncogene Proteins c-fosAnimalsNeoplasmsTumor Microenvironment
FOSL1: The core regulatory hub of tumor-neural interactions and its clinical translational prospects.
Niu Pu, Xitong Bo, Haimin Lu, Fuxiang Chen, Yilong Zhou, Qiong Cheng
Published: 202510.1016/j.intimp.2025.115645
Abstract
As a core AP-1 transcription factor, FOS like-1 (FOSL1) drives cell proliferation, differentiation, transformation, and tumorigenesis by regulating downstream targets via heterodimer formation. Pan-cancer analyses confirm its characteristic overexpre…
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