International immunopharmacologyAnimalsHippocampusNeuronsMitochondriaDiabetes Mellitus
GPR75 knockdown alleviates mitochondrial dysfunction in hippocampal neurons via AMPK pathway in diabetic mice.
Mengren Liu, Lihua Liu, Wenqiang Liu, HongDan Yu, Shengxue Yu, Zihao Liu, Yali Wang, Xinyuan Chen, Quanling Miao, Yirong Yuan, Wei Dai, Jiawei Hu, Na Zhang, Jiaheng Sui, Xuezheng Liu
Published: 202510.1016/j.intimp.2025.115638
Abstract
Diabetic cognitive dysfunction (DCD) is widely acknowledged as a cerebral complication of diabetes mellitus involving hippocampal neuronal damage caused by mitochondrial dysfunction. G protein-coupled receptor 75 (GPR75) is an orphan receptor associa…
Preview only. Read the full abstract at the source