International immunopharmacologyAnimalsMesenchymal Stem CellsFemaleExosomesMicroRNAs
Experimental investigation of adipose-derived mesenchymal stem cell-derived exosomes in the treatment of osteoporosis via the hsa_circ_0028877/miR-4728-3p/PTCH1 axis.
Jianqiao Li, Qingsong Gu, Yiheng Li, Yifan Gu, Yuhu Chen, Linhui Wang, Ziru Wang, Yicong Wang, Min Yang
Published: 202510.1016/j.intimp.2025.115625
Abstract
BACKGROUND: hsa_circ_0028877 may serve as a biomarker for postmenopausal osteoporosis (PMOP) based on bioinformatics analysis; nevertheless, the underlying mechanism remains ambiguous. ADSCs-derived exosomes (ADSCs-exos), as an innovative cell-free t…
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