International immunopharmacologyHumansSingle-Chain AntibodiesAntibodiesBispecificAnimals
Engineering scFv immunotherapies: From CAR T cells to bispecific antibodies.
Mohammad Chand Jamali, Amged Gaffer Mostafa Gaffer, Hakeem Ghani Hassan, Sana Abdul-Jabbar Ali, Mahaboob Khan Sulaiman, Anam Tariq, Nasrin Mansuri, Ashit Kumar Dutta, Mustafa Mudhafar
Published: 202510.1016/j.intimp.2025.115597
Abstract
Single-chain variable fragments (scFvs) have become indispensable tools in cancer immunotherapy due to their high specificity, modularity, and cost-effective production. These engineered antibody fragments enable precise targeting of tumor antigens,…
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