Immunity
Commensal-derived trehalose monocorynomycolate triggers γδ T cell-driven protective ocular barrier immunity.
Xiaoyan Xu, Yannis E Rigas, Mary J Mattapallil, Jing Guo, Keiko Sakamoto, Keisuke Nagao, Vijayaraj Nagarajan, Eric Bohrnsen, Crystal Richards, Akriti Gupta, Guillaume Gaud, Paul E Love, Timothy Jiang, Amy Zhang, Biying Xu
Published: 202610.1016/j.immuni.2025.12.007
Abstract
Commensals shape host physiology through molecular crosstalk with host receptors. Identifying specific microbial factors that causally influence host immunity is key to understanding homeostasis at the host-microbe interface and advancing microbial-b…
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