ImmunityAnimalsMacaca mulattaAllelesGenetic VariationGenomics
Population-level genomic analysis of immunoglobulin loci variation in rhesus macaques reveals extensive germline diversity.
Ayelet Peres, Amit A Upadhyay, Vered Klein, Swati Saha, Oscar L Rodriguez, Zachary M Vanwinkle, Kirti Karunakaran, Amanda Metz, William Lauer, Mark C Lin, Timothy Melton, Lukas Granholm, Pazit Polak, Samuel M Peterson, Eric J Peterson
Published: 202610.1016/j.immuni.2025.12.002
Abstract
Rhesus macaques (RMs) are a vital model for studying human disease and are invaluable to preclinical vaccine research, particularly for the study of broadly neutralizing antibody responses. Such studies require robust genetic resources for antibody-e…
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