ImmunityMultiple SclerosisT-LymphocytesRegulatoryHumansAnimals
A Notch too far: Treg plasticity in multiple sclerosis.
Justine Fiefvet, Lidia Yshii
Published: 202510.1016/j.immuni.2025.10.017
Abstract
Regulatory T cells can play conflicting roles in autoimmune inflammation. In this issue of Immunity, Benamar et al. reveal that gut-microbiota-induced Notch3+ regulatory T cells migrate to the central nervous system in multiple sclerosis and transiti…
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