International journal of radiation oncology, biology, physics
Stereotactic Body Radiation Therapy Augmented Checkpoint Inhibitor Immunotherapy Response in Heavily Pretreated Metastatic Osteosarcoma.
Chuanying Zhu, Yichen Xu, Junxiang Wen, Zhusheng Zhang, Tao Liang, Xiaoyan Chen, Xue Wang, Qi Liu, Beichen Wang, Yucheng Fu, Zhuochao Liu, Jun Wang, Xiaoqing Yang, Yu Cai, Keke Li
Published: 202510.1016/j.ijrobp.2025.11.042
Abstract
PURPOSE: Immunotherapy for relapsed/refractory (R/R) osteosarcoma has shown limited success because of its immunosuppressive microenvironment. Recent evidence suggests stereotactic body radiation therapy (SBRT) as not only a local therapy but also a…
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