International journal of radiation oncology, biology, physics
A Novel Focal Duodenal Radiation Injury Model Reveals Dose-, Time-, and Spatially Dependent Microbiome Perturbations After Radiation Injury.
LeMoyne Habimana-Griffin, Jerome Prusa, Bin Wang, Lori Strong, Jie Ning, Erick S Ramirez Tovar, Kelsey Toth, Blake Butler, Francisco J Reynoso, Stephanie Markovina, Matthew A Ciorba, Gautam Dantas
Published: 202510.1016/j.ijrobp.2025.11.011
Abstract
PURPOSE: The duodenum is a key organ at risk during sterotactic ablative radiotherapy (SABR). Understanding mechanisms of radiation-induced intestinal injury (RIII) could reveal novel strategies to reduce SABR toxicities. The gut microbiome contribut…
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