Atypical ocular bartonellosis: A case report.

Objectives: To report a case of chorioretinitis without papilledema caused by Bartonella henselae in an immunocompetent patient. Observations: A 27-year-old female patient with a history of multiple cat scratches presented on August 28, 2025, with a gradual decline in visual acuity in her right eye. This decline had been developing for 3 weeks following scratches from cats and was accompanied by a fever of 39°C. Optical coherence tomography revealed serous retinal detachment with associated epithelial detachment. Fluorescein angiography showed a hyperfluorescent perimacular focus in the superior temporal region, consistent with chorioretinitis characterized by star-shaped macular exudates, and there was no evidence of papilledema. HIV-1 and 2 serology was negative. Serum protein electrophoresis returned normal results, and the HbA1c level was 5.5%. Serology for B. henselae was positive (immunoglobulin [Ig]G and IgM) with titers greater than 1:1280 and 1:1200. The treatment plan included doxycycline (100 mg every 12 hours) for 6 weeks and rifampicin (300 mg every 12 hours) with corticosteroid therapy (1 mg/kg) for 4 weeks. Fluorescein angiography conducted 6 weeks after treatment showed a hypofluorescent area in the superior temporal region of the macula, indicating that the star-shaped macular exudates had disappeared. The patient reported improved visual acuity, although they experienced slight blurred vision in the right eye. Conclusions: Ocular bartonellosis can lead to unusual eye damage, specifically chorioretinitis, even in the absence of papilledema.