International journal of pharmaceutics
A novel epidermal mimicking phospholipid vesicle-based permeation assay: EpiPVPA for in vitro permeation evaluation.
Yuzhe Wang, Lu Sheng, Lin Bu, Huijuan Li, Jianxin Wu, Qing Huang
Published: 202610.1016/j.ijpharm.2026.126595
Abstract
Phospholipid vesicle-based permeation assay (PVPA) is widely applied as in vitro skin alternative model by mimicking stratum corneum to evaluate the transdermal application of drugs and chemicals. However, it is composed of lipid components only, whi…
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