Bone-targeting lipid-polymer hybrid nanoparticles for less invasive, injectable local antibiotic treatment of bone infections by methicillin-resistant Staphylococcus aureus (MRSA).

Effective treatment of osteomyelitis caused by methicillin-resistant Staphylococcus aureus (MRSA) requires sufficiently high antibiotic concentrations at the infected bone sites. Local drug therapy such as antibiotic-impregnated beads or cement is a…

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