International journal of pharmaceutics
Cysteamine-eluting contact lenses: integrating in vitro, in vivo, and in silico approaches for ocular drug delivery.
Anuj Chauhan, Sarbani Hazra, Brock Matter, Pankaj Kumar Sharma, Shilpa George, Aishee Dey, Bommanahalli Nagaraju Kumara, Uday B Kompella
Published: 202510.1016/j.ijpharm.2025.126528
Abstract
The objective of this study was to develop vitamin E nanobarrier contact lenses that can sustain the delivery of an equivalent amount of cysteamine to the cornea as eight drops per day regimen used in treating cystinosis. Senofilcon A lenses (14.0 mm…
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