International journal of pharmaceuticsNanofibersPramipexoleParkinson DiseaseAdministrationSublingual
Development of sublingual films and electrospun nanofibers of pramipexole for the immediate relief of dyskinesias in Parkinson's disease.
Bianca Costa Bernardo Port, Rodrigo Henrique Saatkamp, Marina Gomes, Júlia Elizabeth Pigatto Stringhi, Gabriela Schneider Rauber, Alexandre Luis Parize, Thiago Caon
Published: 202610.1016/j.ijpharm.2025.126496
Abstract
Oral levodopa/carbidopa tablets remain the gold standard therapy for Parkinson's disease; however, long-term administration of these drugs has been associated with dyskinesias and "on-off" motor fluctuations. Non-ergot dopaminergic agonists such as p…
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