International journal of pharmaceuticsLactoferrinFerroptosisAnimalsFemaleHumans
Lactoferrin-modified niclosamide lipid nanocarriers reprogram ferroptosis and antioxidant networks for breast cancer suppression.
Rana K Mahmoud, Riham M El-Moslemany, Basant A Abou-Taleb, Nesrine S El-Mezayen, Ashraf K Awaad, Magda A El-Massik
Published: 202610.1016/j.ijpharm.2025.126485
Abstract
Repurposing niclosamide (Nic), an FDA-approved anthelmintic with emerging anticancer potential, offers a promising strategy for breast cancer therapy. However, its clinical translation is limited by poor solubility and bioavailability. In this study,…
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