International journal of pharmaceuticsAnimalsMelittenFemaleMiceCell Line
Melittin-Clonidine peritumoral injection gel for cold tumor: exposing tumor antigens and reducing immunosuppressive pressure on immune cells.
Anping Zhang, Hao Wu, Lingchang Li, Xin Jin, Xiaobin Tan, Huixia Lv, Jie Song, Tao Qian, Zhenhai Zhang
Published: 202610.1016/j.ijpharm.2025.126391
Abstract
Immunotherapy has revolutionized the treatment of cancer by activated the immune system to achieve durable responses. Despite these successes, its efficacy remains largely constrained in immunologically "cold" tumors, characterized by poor T-cell inf…
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