International journal of pharmaceuticsMolecular Dynamics SimulationDNASingle-StrandedDependovirusCapsid
Thermal stability and dynamics of ssDNA loaded adeno-associated viral capsids: A coarse-grained molecular dynamics simulations.
Tibo Duran, Shivangi Naik, Willow DiLuzio, Nermin Ibreljic, Arani Chanda, Bodhisattwa Chaudhuri
Published: 202610.1016/j.ijpharm.2025.126378
Abstract
The study investigated the structural breakdown as a function of temperature and potential genome release of adeno-associated virus (AAV) in an aqueous environment through coarse-grained molecular dynamics (CG-MD) simulations. The factors and mechani…
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