International journal of pharmaceuticsHumansHypertrophyAerosolsAdministrationInhalation
Comparative investigation of the transport and deposition of nebulized particles in pediatric mouth-throat airways with tonsil hypertrophy at different severity levels.
Feilun Yang, Ruiping Ma, Yusheng Wang, Zehui Li, Yewen Shi, Xin Feng, Guoxi Zheng, Xiaoyong Ren, Shaokoon Cheng, Jingliang Dong, Ya Zhang
Published: 202510.1016/j.ijpharm.2025.126365
Abstract
BACKGROUND: Pediatric allergic asthma necessitates efficient aerosol drug delivery through the mouth-throat (MT) airway. Tonsil hypertrophy (TH), a common comorbidity, causes oropharyngeal obstruction, potentially compromising inhalation therapy. Thi…
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