International journal of pharmaceuticsMembranesArtificialCapillary ElectrochromatographyPharmaceutical PreparationsPermeability
Modelling lung permeability of pharmaceuticals: The effectiveness of biomimetic open tubular capillary electrochromatography and immobilised artificial membrane chromatography coupled with mass spectrometry.
Amy Dillon, Dumidu Perera, Dorota Orzel, Susanne K Wiedmer, Giacomo Russo
Published: 202610.1016/j.ijpharm.2025.126356
Abstract
In this study, the potential of mass spectrometry (MS) -compatible biomimetic chromatography (BMC) was explored to assess drug permeability across biological membranes, pioneering a comparison of its application to model pulmonary absorption. Two BMC…
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