International journal of pharmaceuticsHumansOxidation-ReductionAntineoplastic AgentsAnimalsProdrugs
Chalcogen-bond engineered redox-responsive nano-prodrugs for anticancer therapy.
Guobing Feng, Guangfei Wei, Jialei Luo, Dan Zhang, Leping Hou, Mengyu Xing, Rui Guo, Shuang Xu, Ying Luo, Gaoyi Yang, Yuezhou Zhang
Published: 202510.1016/j.ijpharm.2025.126355
Abstract
The distinct redox imbalance in malignant cells, characterized by elevated reactive oxygen species and glutathione levels compared to normal tissues, establishes a therapeutic window for chemotherapeutic intervention through exploitation of the tumor…
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