Binary lipid system-based granules with undissolved drug crystals enhance oral bioavailability by preventing degradation and improving permeability.

Conventional oral drug delivery systems, such as lipid-based formulations and nanoparticles, require drugs to fully dissolve in excipients to improve solubility and bioavailability. However, many drugs, including olmesartan medoxomil (OLM), an ester…

Preview only. Read the full abstract at the source