International journal of pharmaceuticsAnimalsEzetimibeNon-alcoholic Fatty Liver DiseasePolylactic Acid-Polyglycolic Acid CopolymerMale
Targeted hepatic delivery of ezetimibe via red blood cell-coated nanoparticles for the treatment of non-alcoholic fatty liver disease through inflammation modulation.
Ozgur Esim, Seyma Adatepe, Okan Ali Aksoy, Berk Alp Goksel, Tugba Yilmaz, Baris Baykal, Çigdem Yucel, Sevilay Erdogan Kablan, Cemil Can Eylem, Engin Kocak, Hakan Erdogan, Cansel Kose Ozkan, Emirhan Nemutlu, Ayhan Savaser, Yalçın Ozkan
Published: 202510.1016/j.ijpharm.2025.126241
Abstract
This study investigates the potential of red blood cell (RBC) membrane-coated, ezetimibe-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles for targeted therapy of non-alcoholic fatty liver disease (NAFLD). PLGA nanoparticles were fabricated a…
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