International journal of pharmaceuticsExcipientsHumansBotulinum ToxinsType ADrug Stability
A novel peptide excipient stabilizes DaxibotulinumtoxinA.
Shaoqiu Zhuo, G Reza Malmirchegini, Conor J Gallagher
Published: 202510.1016/j.ijpharm.2025.126238
Abstract
Surface adsorption of proteins in bulk drug product formulations and loss of protein structural integrity during manufacturing processes can diminish drug potency. In formulations containing low biologic drug substance, such as botulinum toxin type A…
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