International journal of pharmaceuticsBrain NeoplasmsDrug Delivery SystemsAntineoplastic AgentsHumansCatheters
Evaluation of drug distributions in brain tumor therapy: An in silico comparative study of multi-side-hole and standard end-hole catheters in convection-enhanced delivery.
Ying Wang, Aili Zhang, Limei Cao, Ziyi Lou, Xinhui Si, Xuelan Zhang, Wei Wang, Jing Zhu
Published: 202510.1016/j.ijpharm.2025.126230
Abstract
Convection-enhanced delivery (CED) is a promising technique for treating brain tumors by enabling drugs to bypass the blood-brain barrier (BBB). The types of catheters and physicochemical properties of drugs both influence drug distribution within tu…
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